I had a Thrustmaster HOTAS setup circa '08 for about a week.
Overall, I was not impressed.
Weight was good. It felt like a good stick, had a fair amount of mass to it. It felt substantial and durable. However, something like 1/8 of the controls were broken to some degree. Research online at the time showed that enthusiasts were essentially saying "Yeah, buy one if you want to replace all the guts." I ended up sending it back and going with a $45 cheapass joystick that was a much, MUCH better value for the price.
Given that it was almost 8 years ago, maybe Thrustmaster has gotten their shit together in the meantime, but I'd suggest a bit of research to be sure.
Personally, I'm in the market for a good controller setup but haven't really started digging too deep yet. It's mostly going to be for Star Citizen / ED, but I'm thinking the way to go is 3-axis joystick, throttle, and then 2-axis pedals. Pedals are planar movement up/down & L/R, throttle is forward/retro thrust and a shit-ton of systems management buttons, and then the joystick is targetting/fire control/rotational movement. The CH throttle looks pretty hot for the thumb joystick and button layout, the pedals look...well...adequate, I guess, but the joystick is a total nonstarter on that front.
Honestly, I'm sort of surprised that the pickings are as slim as they are. Figured there'd be some pretty clear suites out there for just this sort of thing.